Projects

Current Projects

Clarification of the structures and regulatory mechanisms that control the formation of vesicles that host SM pathways in fungi; and expand the knowledge of sorting signals
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New antifungal compounds
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Mechanisms of microbial communication leading to activation of silent gene clusters
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N. N. 7
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RNA cargo of extracellular vesicles
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Molecular Mechanisms of lipid raft formation
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Communication between bacteria and fungi by secondary metabolites
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Former Projects

Acute and chronic Aspergillus infection in mice studied by PET-CT and comparative gene expression
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Lysine biosynthesis in Aspergillus fumigatus
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Post-translational modifications and pathogenicity of the human pathogenic fungus Aspergillus fumigatus
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Cryo-stress of filamentous fungi
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Secretome analysis/pathogenicity mechanisms of Arthroderma benhamiae
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Prediction of gene regulatory networks involved in the differentiation, secondary metabolism and cross talk of Aspergillus nidulans
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Regulation of cell wall integrity signalling by mitogen-activated protein kinase MpkA in Aspergillus fumigatus
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The hypoxic (low-oxygen) response of the pathogenic mould Aspergillus fumigatus and its relevance to pathogenicity
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The genome of the endofungal bacterium Burkholderia rhizoxinica
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Bioinformatic investigation and prediction of gene regulatory elements in pathogenic fungi
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Integrated genome-wide data analysis by ensemble learning methods to understand infection processes
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Identification of immunogenic components of Aspergillus fumigatus for vaccine development
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Identifying the pulmonary phagocytic network of mice infected with Aspergillus fumigatus
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A surface hydrophobin in ectomycorrhiza interaction
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Molecular mechanisms of the interaction between Aspergillus fumigatus and alveolar macrophages
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Novel molecular mechanisms of iron sensing and homeostasis in Aspergillus fumigatus
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Functionality and plasticity of bacterial polyketide synthases
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The role of virulence determinants of the human pathogenic fungus Aspergillus fumigatus in the defense against fungivorous amoeba
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Heterologous expression of silent gene clusters in fungi
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Oxidative inactivation of primary metabolism pathways in the human pathogenic fungus Aspergillus fumigatus
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Developing molecular tools for the de novo assembling of biosynthetic routes
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Development of a user-friendly heterologous expression system and its applications for natural product biosynthesis
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Engineering of polyketide production routes in the amoeba Dictyostelium discoideum
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Communication via extracellular vesicles between immune cells and the human-pathogenic fungus Aspergillus fumigatus
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Adhäsionsmechanismen von Escherichia coli auf Titanoberflächen
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