Prof. Dr. Christine Skerka
N. N. 4
The contribution of spore surface proteins of Lichtheimia corymbifera during infection of the host cells
The role of CFHR proteins in human autoimmune diseases
Characterization of the immediate early response of human dendritic cells to Candida albicans
Complement evasion of human pathogenic microorganisms
Role of human regulatory proteins of the complement system in health and disease
Functional characterization of the soluble complement receptor type II (CR2/CD21) in infection
Interaction of complement proteins and acute phase proteins in inflammatory processes
Characterisation of human complement regulators to Plasmodium falciparum
(2017) Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. J Neuroinflammation 14(1), 4.
(2016) FHR3 Blocks C3d-Mediated Coactivation of Human B Cells. J Immunol ,
(2015) Sequence variations and protein expression levels of the two immune evasion proteins Gpm1 and Pra1 influence virulence of clinical Candida albicans isolates. PLoS One 10(2), e0113192.
(2015) The role of complement in C3 glomerulopathy. Mol Immunol 67(1), 21-30.
(2014) Complement factor H-related hybrid protein deregulates complement in dense deposit disease. J Clin Invest 124(1), 145-155.
(2014) Tuf of Streptococcus pneumoniae is a surface displayed human complement regulator binding protein. Mol Immunol 62(1), 249-264.
(2013) Human factor H-related protein 2 (CFHR2) regulates complement activation. PLoS One 8(11), e78617.
(2013) Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis. J Am Soc Nephrol 24(1), 53-65.
(2013) Glycerol-3-phosphate dehydrogenase 2 is a novel factor H-, factor H-like protein 1-, and plasminogen-binding surface protein of Candida albicans. J Infect Dis 207(4), 594-603.
(2013) Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans. Mol Immunol 56(3), 161-169.
(2012) Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b. PLoS One 7(10), e47638.
(2011) Combined C3b and factor B autoantibodies and MPGN type II. N Engl J Med 365(24), 2340-2342.
(2011) β₂-glycoprotein I, the major target in antiphospholipid syndrome, is a special human complement regulator. Blood 118(10), 2774-2783.
(2011) The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem 286(10), 8021-8029.
(2011) Immune escape of the human facultative pathogenic yeast Candida albicans: the many faces of the Candida Pra1 protein. Int J Med Microbiol 301(5), 423-430.
(2010) An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD). Hum Mol Genet 19(23), 4694-4704.
(2010) Secreted pH-regulated antigen 1 of Candida albicans blocks activation and conversion of complement C3. J Immunol 185(4), 2164-2173.
(2009) Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation. Blood 114(12), 2439-2447.
(2009) Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H. Cell Death Differ 16(12), 1630-1640.