Publications

Sundaram S, Kim HJ, Bauer R, Thongkongkaew T, Heine D, Hertweck C (2018) On-line Polyketide Cyclization into Diverse Medium-Sized Lactones by a Specialized Ketosynthase Domain. Angew Chem Int Ed Engl 57(35), 11223-11227. Details PubMed

Kugel S, Baunach M, Baer P, Ishida-Ito M, Sundaram S, Xu Z, Groll M, Hertweck C (2017) Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification. Nat Commun 8, 15804. Details PubMed

Sundaram S, Hertweck C (2016) On-line enzymatic tailoring of polyketides and peptides in thiotemplate systems. Curr Opin Chem Biol 31, 82-94. Details PubMed

Heine D, Sundaram S, Bretschneider T, Hertweck C (2015) Twofold polyketide branching by a stereoselective enzymatic Michael addition. Chem Commun (Camb) 51(48), 9872-9875. Details PubMed

Sundaram S, Heine D, Hertweck C (2015) Polyketide synthase chimeras reveal key role of ketosynthase domain in chain branching. Nat Chem Biol 11(12), 949-951. Details PubMed

Heine D, Bretschneider T, Sundaram S, Hertweck C (2014) Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles. Angew Chem Int Ed Engl 53(43), 11645-11649. Details PubMed