Dirk Hoffmeister

Prof. Dr. Dirk Hoffmeister

Phone: +49 3641 532-1310 Email: dirk.hoffmeister@leibniz-hki.de Website: www.leibniz-hki.de/de/pharmazeutische-mikrobiologie.html

Projects

Current Projects

Biosynthesis of basidiomycete polyenes
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Elucidation of the biosynthesis of Sphingolipid inhibitors in Aspergillus fumigatus and Aspergillus niger
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Compounds from neglected bacteria and target analysis
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The biosynthesis, biochemistry and physiology of coenzyme 3PG-F420
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The biochemistry and physiology of the redox cofactor mycofactocin
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Former Projects

Investigation of secondary metabolites from insect-associated microbes and their contribution to insect homeostasis and defense
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Investigation of polyketide biosynthesis in agaricomycetes
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The role of Desulfitobacterium spp. in the global network of O-demethylation in soil
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Publications

Schwenk D, Brandt P, Blanchette RA, Nett M, Hoffmeister D (2016) Unexpected Metabolic Versatility in a Combined Fungal Fomannoxin/Vibralactone Biosynthesis. J Nat Prod 79(5), 1407-1414. Details PubMed

Shah F, Schwenk D, Nicolás C, Persson P, Hoffmeister D, Tunlid A (2015) Involutin Is an Fe3+ Reductant Secreted by the Ectomycorrhizal Fungus Paxillus involutus during Fenton-Based Decomposition of Organic Matter. Appl Environ Microbiol 81(24), 8427-8433. Details PubMed

Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C (2014) Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion. Angew Chem Int Ed Engl 53(49), 13409-13413. Details PubMed

Schwenk D, Nett M, Dahse HM, Horn U, Blanchette RA, Hoffmeister D (2014) Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete. J Nat Prod 77(12), 2658-2663. Details PubMed

Elliott CE, Callahan DL, Schwenk D, Nett M, Hoffmeister D, Howlett BJ (2013) A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans. Fungal Genet Biol 53, 50-58. Details PubMed

Forseth RR, Amaike S, Schwenk D, Affeldt KJ, Hoffmeister D, Schroeder FC, Keller NP (2013) Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus. Angew Chem Int Ed Engl 52(5), 1590-1594. Details PubMed

Fernandez-Fueyo E, Ruiz-Dueñas FJ, Ferreira P, Floudas D, Hibbett DS, Canessa P, Larrondo LF, James TY, Seelenfreund D, Lobos S, Polanco R, Tello M, Honda Y, Watanabe T, Watanabe T, Ryu JS, San RJ, Kubicek CP, Schmoll M, Gaskell J, Hammel KE, St John FJ, Vanden Wymelenberg A, Sabat G, Splinter BonDurant S, Syed K, Yadav JS, Doddapaneni H, Subramanian V, Lavín JL, Oguiza JA, Perez G, Pisabarro AG, Ramirez L, Santoyo F, Master E, Coutinho PM, Henrissat B, Lombard V, Magnuson JK, Kües U, Hori C, Igarashi K, Samejima M, Held BW, Barry KW, LaButti KM, Lapidus A, Lindquist EA, Lucas SM, Riley R, Salamov AA, Hoffmeister D, Schwenk D, Hadar Y, Yarden O, de Vries RP, Wiebenga A, Stenlid J, Eastwood D, Grigoriev IV, Berka RM, Blanchette RA, Kersten P, Martinez AT, Vicuna R, Cullen D (2012) Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis. Proc Natl Acad Sci U S A 109(14), 5458-5463. Details PubMed

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