Marc Thilo Figge

Prof. Dr. Marc Thilo Figge

Phone: +49 3641 532-1416 Email: thilo.figge@leibniz-hki.de Website: www.leibniz-hki.de/de/angewandte-systembiologie.html

Projects

Current Projects

Virtual infection model for Aspergillus fumigatus in human alveoli
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Investigation of host-pathogen interactions using individual-based modeling
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Population-based modeling of infection processes
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From single-cell to whole-organ monitoring: Morphokinetic characterisation of infection via quantitative image analysis
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Former Projects

Automated analysis of dynamic properties in biological systems from image data
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Functional characterization of the soluble complement receptor type II (CR2/CD21) in infection
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Automated image analysis of the interaction between Lichtheimia spp. and murine alveolar macrophages
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Publications

Brandes S, Dietrich S, Hünniger K, Kurzai O, Figge MT (2017) Migration and interaction tracking for quantitative analysis of phagocyte-pathogen confrontation assays. Med Image Anal 36, 172. Details PubMed

Buhlmann D, Eberhardt HU, Medyukhina A, Prodinger WM, Figge MT, Zipfel PF, Skerka C (2016) FHR3 Blocks C3d-Mediated Coactivation of Human B Cells. J Immunol , Details PubMed

Brandes S, Mokhtari Z, Essig F, Hünniger K, Kurzai O, Figge MT (2015) Automated segmentation and tracking of non-rigid objects in time-lapse microscopy videos of polymorphonuclear neutrophils. Med Image Anal 20(1), 34-51. Details PubMed

Essig F, Hünniger K, Dietrich S, Figge MT, Kurzai O (2015) Human neutrophils dump Candida glabrata after intracellular killing. Fungal Genet Biol 84, 37-40. Details PubMed

Zang E, Brandes S, Tovar M, Martin K, Mech F, Horbert P, Henkel T, Figge MT, Roth M (2013) Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets. Lab Chip 13(18), 3707-3713. Details PubMed

Mech F, Thywissen A, Guthke R, Brakhage AA, Figge MT (2011) Automated image analysis of the host-pathogen interaction between phagocytes and Aspergillus fumigatus. PLoS One 6(5), e19591. Details PubMed

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