
Dr. Olaf Kniemeyer
Phone: +49 3641 532-1071 Email: olaf.kniemeyer@leibniz-hki.de Website: www.leibniz-hki.de/de/stress-und-immun-proteomforschung.h
Projects
Current Projects
New antifungal compounds
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The impact of redox regulation on the stress response of Aspergillus fumigatus and its role in host-pathogen interaction
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Former Projects
Cryo-stress of filamentous fungi
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The hypoxic (low-oxygen) response of the pathogenic mould Aspergillus fumigatus and its relevance to pathogenicity
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Identification of immunogenic components of Aspergillus fumigatus for vaccine development
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Investigation of the stress response system of A. fumigatus by redox proteomics
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The role of Apolipoprotein E in the innate immune system
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Publications
(2016) Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature 532(7597), 64-68. Details PubMed
(2015) Insights into the cellular responses to hypoxia in filamentous fungi. Curr Genet 61(3), 441-455. Details PubMed
(2015) Influence of zygomycete-derived D'orenone on IAA signaling in Tricholoma-spruce ectomycorrhiza. Environ Microbiol , Details PubMed
(2015) Tricholoma vaccinum host communication during ectomycorrhiza formation. FEMS Microbiol Ecol 91(11), Details PubMed
(2014) Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence. Front Microbiol 5, 469. Details PubMed
(2013) Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus. Front Microbiol 4, 141. Details PubMed
(2012) The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells. Eukaryot Cell 11(5), 673-682. Details PubMed
(2012) Systems biology of fungal infection. Front Microbiol 3, 108. Details PubMed
(2012) Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression. BMC Genomics 13, 519. Details PubMed
(2011) On the way toward systems biology of Aspergillus fumigatus infection. Int J Med Microbiol 301(5), 453-459. Details PubMed
(2011) Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol 12(1), R7. Details PubMed
(2010) Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLoS Pathog 6(4), e1000873. Details PubMed
(2010) Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin. Proteomics 10(17), 3097-3107. Details PubMed
(2010) Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus. J Proteome Res 9(7), 3427-3442. Details PubMed
(2009) Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus. Proteomics 9(5), 1407-1415. Details PubMed
(2008) Normalisation of 2D DIGE data - on the way to a standard operating procedure. BIRD08 Schriftenreihe Informatik 26, 55-64. Details
(2007) Discovery of gene regulatory networks in Aspergillus fumigatus. Lect Notes Bioinf 4366, 22-41. Details