Cannabinoids from amoebae

New publication in Nature Biotechnology

January 18, 2022

The unicellular amoeba Dictyostelium discoideum can form a multicellular association and build fruiting bodies that release spores. Source: Falk Hillmann, Leibniz-HKI

ILRS doctoral researcher Christin Reimer and alumnus Johann Kufs are first authors of a study that developed a new method to produce complex natural products in amoebae. These polyketides include various antibiotics but also olivetolic acid, a precursor of the herbal active ingredient tetrahydrocannabinol (THC). The results were published in Nature Biotechnology. Congratulations to Johann and Christin!

Link to the press release:

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