Sarah Niehs

Sarah Niehs

Email: sarah.niehs@leibniz-hki.de

Genomics-based search for natural products in neglected bacteria

Publications

Dose B, Ross C, Niehs SP, Scherlach K, Bauer JP, Hertweck C (2020) Food-Poisoning Bacteria Employ a Citrate Synthase and a Type II NRPS To Synthesize Bolaamphiphilic Lipopeptide Antibiotics. Angew Chem Int Ed Engl , Details PubMed

Niehs SP, Dose B, Richter S, Pidot SJ, Dahse HM, Stinear TP, Hertweck C (2020) Mining Symbionts of Spider-Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones. Angew Chem Int Ed Engl , Details PubMed

Niehs SP, Kumpfmüller J, Dose B, Little RF, Ishida K, Florez LV, Kaltenpoth M, Hertweck C (2020) Insect-Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non-Canonical Polyketide Chain Termination Angew Chem Int Ed [Epub ahead of print] Details PubMed

Niehs SP, Dose B, Scherlach K, Pidot SJ, Stinear TP, Hertweck C (2019) Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis. ACS Chem Biol 14(8), 1811-1818. Details PubMed

Dose B, Niehs SP, Scherlach K, Flórez LV, Kaltenpoth M, Hertweck C (2018) Unexpected Bacterial Origin of the Antibiotic Icosalide: Two-Tailed Depsipeptide Assembly in Multifarious Burkholderia Symbionts. ACS Chem Biol 13(9), 2414-2420. Details PubMed

Niehs S, Dose B, Scherlach K, Roth M, Hertweck C (2018) Genomics-Driven Discovery of a Symbiont-Specific Cyclopeptide from Bacteria Residing in the Rice Seedling Blight Fungus. Chembiochem 19(20), 2167-2172. Details PubMed

Niehs SP, Scherlach K, Hertweck C (2018) Genomics-driven discovery of a linear lipopeptide promoting host colonization by endofungal bacteria. Org Biomol Chem 16(37), 6967-6974. Details PubMed

Supervisor

Christian Hertweck

Start of PhD

March 1, 2016

Doctoral Disputation

December 14, 2020

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