Communication via extracellular vesicles between immune cells and the human-pathogenic fungus Aspergillus fumigatus
Extracellular vesicles (EVs) are produced by nearly all cells. They are in particular important for the exchange of information between immune cells and microbial pathogens. We focus on the characterisation of EVs of immune cells like macrophages and neutrophils and their effects on pathogens and other immune cells. EVs will be characterised for small RNAs and proteins and their effects on targets. This research might also have implications for the improvement of diagnosis and therapy.
(2020) The dynamic surface proteomes of allergenic fungal conidia J Proteome Res 19(5), 2092-2104.
Start of PhD
January 17, 2018