Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen.
(2012) Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen. Angew Chem Int Ed Engl 51(52), 13173-13177. PubMed
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Molecular basis of bacterial-mushroom interactions
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The genome of the endofungal bacterium Burkholderia rhizoxinica
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Abstract
Caught in the act: imaging mass spectrometry of a button mushroom infected with the soft rot pathogen Janthinobacterium agaricidamnosum in conjunction with genome mining revealed jagaricin as a highly antifungal virulence factor that is not produced under standard cultivation conditions. The structure of jagaricin was rigorously elucidated by a combination of physicochemical analyses, chemical derivatization, and bioinformatics.
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doi: 10.1002/anie.201206658 PMID: 23161559
