Mattthias Brock

Dr. Mattthias Brock

Phone: +49 3641 532-1710 Email:


Former Projects

Lysine biosynthesis in Aspergillus fumigatus

Interactions and regulatory networking of MADS-domain Transcription factors in model plants (Arabidopsis thaliana)


Brunke S, Seider K, Richter ME, Bremer-Streck S, Ramachandra S, Kiehntopf M, Brock M, Hube B (2014) Histidine degradation via an aminotransferase increases the nutritional flexibility of Candida glabrata. Eukaryot Cell 13(6), 758-765. Details PubMed

Ramachandra S, Linde J, Brock M, Guthke R, Hube B, Brunke S (2014) Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. PLoS One 9(3), e92734. Details PubMed

Fazius F, Zaehle C, Brock M (2013) Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production. Appl Microbiol Biotechnol 97(9), 3763-3772. Details PubMed

Fazius F, Shelest E, Gebhardt P, Brock M (2012) The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate. Mol Microbiol 86(6), 1508-1530. Details PubMed

Fleck CB, Schöbel F, Brock M (2011) Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization. Int J Med Microbiol 301(5), 400-407. Details PubMed

Müller S, Fleck CB, Wilson D, Hummert C, Hube B, Brock M (2011) Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases. Environ Microbiol 13(6), 1534-1548. Details PubMed

Schöbel F, Ibrahim-Granet O, Avé P, Latgé JP, Brakhage AA, Brock M (2007) Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis. Infect Immun 75(3), 1237-1244. Details PubMed

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