Gerald Lackner

Gerald Lackner

Projects

Current Projects

Elucidating the role of Candida albicans Ece1 peptides
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The biosynthesis, biochemistry and physiology of coenzyme 3PG-F420
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The biochemistry and physiology of the redox cofactor mycofactocin
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Former Projects

The genome of the endofungal bacterium Burkholderia rhizoxinica
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Discovery and biosynthesis of the redox cofactor mycofactocin
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Publications

Graupner K, Lackner G, Hertweck C (2015) Genome Sequence of Mushroom Soft-Rot Pathogen Janthinobacterium agaricidamnosum. Genome Announc 3(2), Details PubMed

Uzum Z, Silipo A, Lackner G, De Felice A, Molinaro A, Hertweck C (2015) Structure, genetics and function of an exopolysaccharide produced by a bacterium living within fungal hyphae. Chembiochem 16(3), 387-392. Details PubMed

Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C (2014) Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion. Angew Chem Int Ed Engl 53(49), 13409-13413. Details PubMed

Moebius N, Üzüm Z, Dijksterhuis J, Lackner G, Hertweck C (2014) Active invasion of bacteria into living fungal cells. Elife 3, e03007. Details PubMed

Scherlach K, Lackner G, Graupner K, Pidot S, Bretschneider T, Hertweck C (2013) Biosynthesis and mass spectrometric imaging of tolaasin, the virulence factor of brown blotch mushroom disease. Chembiochem 14(18), 2439-2443. Details PubMed

Graupner K, Scherlach K, Bretschneider T, Lackner G, Roth M, Gross H, Hertweck C (2012) Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen. Angew Chem Int Ed Engl 51(52), 13173-13177. Details PubMed

Scherlach K, Busch B, Lackner G, Paszkowski U, Hertweck C (2012) Symbiotic cooperation in the biosynthesis of a phytotoxin. Angew Chem Int Ed Engl 51(38), 9615-9618. Details PubMed

Silipo A, Leone MR, Lanzetta R, Parrilli M, Lackner G, Busch B, Hertweck C, Molinaro A (2012) Structural characterization of two lipopolysaccharide O-antigens produced by the endofungal bacterium Burkholderia sp. HKI-402 (B4). Carbohydr Res 347(1), 95-98. Details PubMed

Gee JE, Glass MB, Lackner G, Helsel LO, Daneshvar M, Hollis DG, Jordan J, Morey R, Steigerwalt A, Hertweck C (2011) Characterization of Burkholderia rhizoxinica and B. endofungorum isolated from clinical specimens. PLoS One 6(1), e15731. Details PubMed

Lackner G, Hertweck C (2011) Impact of endofungal bacteria on infection biology, food safety, and drug development. PLoS Pathog 7(6), e1002096. Details PubMed

Lackner G, Moebius N, Hertweck C (2011) Endofungal bacterium controls its host by an hrp type III secretion system. ISME J 5(2), 252-261. Details PubMed

Lackner G, Moebius N, Partida-Martinez L, Hertweck C (2011) Complete genome sequence of Burkholderia rhizoxinica, an Endosymbiont of Rhizopus microsporus. J Bacteriol 193(3), 783-784. Details PubMed

Lackner G, Moebius N, Partida-Martinez LP, Boland S, Hertweck C (2011) Evolution of an endofungal lifestyle: Deductions from the Burkholderia rhizoxinica genome. BMC Genomics 12, 210. Details PubMed

Leone MR, Lackner G, Silipo A, Lanzetta R, Molinaro A, Hertweck C (2010) An unusual galactofuranose lipopolysaccharide that ensures the intracellular survival of toxin-producing bacteria in their fungal host. Angew Chem Int Ed Engl 49(41), 7476-7480. Details PubMed

Lackner G, Möbius N, Scherlach K, Partida-Martinez LP, Winkler R, Schmitt I, Hertweck C (2009) Global distribution and evolution of a toxinogenic Burkholderia-Rhizopus symbiosis. Appl Environ Microbiol 75(9), 2982-2986. Details PubMed

Lackner G, Partida-Martinez LP, Hertweck C (2009) Endofungal bacteria as producers of mycotoxins. Trends Microbiol 17(12), 570-576. Details PubMed

Lackner G, Schenk A, Xu Z, Reinhardt K, Yunt ZS, Piel J, Hertweck C (2007) Biosynthesis of pentangular polyphenols: deductions from the benastatin and griseorhodin pathways. J Am Chem Soc 129(30), 9306-9312. Details PubMed

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