PD Dr. Reinhard Guthke
Phone: +49 3641 532-1083 Email: email@example.com Website: www.leibniz-hki.de/de/systembiologie-und-bioinformatik.ht
Integration of transcriptome and proteome data from human-pathogenic fungi
Automated analysis of dynamic properties in biological systems from image data
Prediction of gene regulatory networks involved in the differentiation, secondary metabolism and cross talk of Aspergillus nidulans
Bioinformatic investigation and prediction of gene regulatory elements in pathogenic fungi
Optimization of the influenza neuraminidase inhibitor therapy by use of secondary bacterial infections
Integrated genome-wide data analysis by ensemble learning methods to understand infection processes
Analysis and interpretation of variance in gene expression data
(2015) Draft Genome Sequence and Gene Annotation of the Entomopathogenic Fungus Verticillium hemipterigenum. Genome Announc 3(1),
(2015) Draft Genome Sequence of the Fungus Penicillium brasilianum MG11. Genome Announc 3(5),
(2015) Draft Genome Sequences of Symbiotic and Nonsymbiotic Rhizopus microsporus Strains CBS 344.29 and ATCC 62417. Genome Announc 3(1),
(2015) Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Res 43(3), 1392-1406.
(2015) FungiFun2: a comprehensive online resource for systematic analysis of gene lists from fungal species. Bioinformatics 31(3), 445-446.
(2014) Interactive exploration of integrated biological datasets using context-sensitive workflows. Front Genet 5, 21.
(2014) Draft Genome Sequence of Streptomyces iranensis. Genome Announc 2(4),
(2014) Within-host influenza dynamics: a small-scale mathematical modeling approach. Biosystems 118, 51-59.
(2014) Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. PLoS One 9(3), e92734.
(2012) Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression. BMC Genomics 13, 519.
(2011) On the way toward systems biology of Aspergillus fumigatus infection. Int J Med Microbiol 301(5), 453-459.
(2011) Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol 12(1), R7.
(2011) Automated image analysis of the host-pathogen interaction between phagocytes and Aspergillus fumigatus. PLoS One 6(5), e19591.
(2011) FungiFun: a web-based application for functional categorization of fungal genes and proteins. Fungal Genet Biol 48(4), 353-358.
(2010) Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin. Proteomics 10(17), 3097-3107.
(2010) Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus. J Proteome Res 9(7), 3427-3442.
(2009) Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus. Proteomics 9(5), 1407-1415.
(2008) Normalisation of 2D DIGE data - on the way to a standard operating procedure. BIRD08 Schriftenreihe Informatik 26, 55-64.
(2008) Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane. Arthritis Res Ther 10(4), R98.
(2007) Discovery of gene regulatory networks in Aspergillus fumigatus. Lect Notes Bioinf 4366, 22-41.